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Neofusicoccum is a fungal plant pathogen belonging to the Botryosphaeriaceae family. While not a cactus clone itself, it is a significant pathogen affecting *Trichocereus* species, most notably the Predominant Cultivar (PC) *Trichocereus pachanoi*. The host plants typically feature 5 to 8 rounded ribs, a light green to glaucous blue-green epidermis, and short, upturned yellowish spines arising from white felted areoles. When infected with Neofusicoccum, the host's epidermis develops dark, sunken fungal cankers and necrotic lesions that compromise the plant's aesthetic and structural integrity. The pathogen is slow-moving and rarely transfers to scions or new pups, though transmission remains possible if left unchecked.
The identification of Neofusicoccum (often spelled “Neofussicoccum” in community discussions) within *Trichocereus* collections was highlighted by community expert Gee Bee in early 2026. The pathogen is known in broader agriculture, but its specific impact on cultivated *Trichocereus* stands, particularly PC during winter, has been documented through community observations. The original environmental source or vector of the pathogen in these collections remains undocumented.
To manage and suppress Neofusicoccum infections, growers must employ targeted chemical controls, as standard organic treatments like sulfur may not be fully effective.